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Specifically designed prospective trials are urgently needed to determine the real prophylactic impact of aspirin, as well as of alternative or concomitant therapeutic strategies such as hydroxychloroquine, statins or DOACS in aPL positive patients.
The prophylactic impact of SCEE against alloxan-instigated reduction in testosterone is because of ameliorative oxidative stress in the testes.
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8 43 44 For instance, a study in Ethiopia found that a shortage of prophylactic antibiotics impacted service quality 21 despite the government's efforts to ensure universal free access to ART and treatment of opportunistic infections.
Economic burden of illness studies quantifying the differences in healthcare costs between CM and EM are particularly important in order to estimate the potential economic impact prophylactic agents may have either through reducing the transition from EM to CM or by facilitating CM remission.
The WHO position paper on HPV vaccines states that as HPV vaccines are prophylactic, the largest impact of vaccination is expected from high coverage of young adolescent girls before first sexual activity and exposure to the viruses, and recommends that females aged 9 or 10 through 13 be the primary target population (World Health Organization, 2009).
In the absence of other data, a decision model has been developed which allows individualized assessment of the impact of prophylactic BSO, bilateral prophylactic mastectomy and HT use on life expectancy in BRCA1/2 carriers at age 30, 35 and 40.
Thus, further studies are needed to investigate whether prophylactic antibiotic use impacts functional outcome.
To evaluate the clinical and economic impact of prophylactic administration of intracameral cefuroxime on cataract surgery.
We perform a study to assess the impact of prophylactic NIV after extubation among patients with severe traumatic brain injury.
To date, there are no studies evaluating the impact of prophylactic vertebroplasty on PJK and PJF incidence at long-term follow-up.
We also present data about the frequency of use and psychosocial impact of prophylactic surgery in this typically young group of women.
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