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Through these efforts, a potent and selective inhibitor of CYP3A, GS-9350 (cobicistat) with improved physiochemical properties was discovered.
In our previous virtual screening campaign, a chemical class of benzene-1,3-dicarboxylic acid 2,5-dimethylpyrrole derivatives exhibiting dual MurD/MurE inhibition properties was discovered.
Soon thereafter, a region with equivalent properties was discovered in birds and mammals to reside in Hensen's node, at the tip of the primitive streak [3] [8] and in the embryonic shield of teleosts [9] [11].
The methodology was applied to the challenging Morita Baylis Hillman (MBH) reaction, and a selective bifunctional catalyst with interesting properties was discovered.[ 16] This method circumvents previous issues with DCC and catalysis by directly screening towards the actual chemical transformation in a kinetic manner.
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Pentacene is a polymer whose semiconducting properties were discovered only recently.
Sources of fatigue dependency in ECC microscopic constituent properties were discovered experimentally.
As-produced hierarchical nanostructures were used as supercapacitor electrodes, and stack-dependent device properties were discovered.
Promoters with novel regulatory properties were discovered or engineered from existing ones.
The relationship between the general strategy and the optimal offline strategy is analyzed, and three properties are discovered.
After its hallucinogenic properties were discovered by Hoffman in 1943, it was used as a tool for modelling schizophrenia in healthy volunteers and taken by some psychiatrists to gain insight into mental illness.
The rumour goes that its tanning properties were discovered by accident in the 1920s when a nurse treating a diabetic patient with DHA accidentally spilled it on his chest while connecting his drip.
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