Therefore, to determine whether genes involved in cancer-specific recurrent translocations exhibit properties of fragile sites, we analyzed three gene pairs from Table 1 (CBFB/MYHMGA1/LAMA4Land4, and MLL/AFF4), and their flanking sequences, for flexibility, A/T content, and the propensity to form stable secondary structures.
Activity of an alleged adenylylsulfate ammonia adenylyltransferase is actually an inherent property of fragile histidine triad proteins (Fhits).
without damaging the morphology and optical properties of the fragile p 6P nanofibers.
Taken together, these results suggest that the extent of sudden fluidization depends primarily on the physical property of the fragile material, whereas the resolidification response is dependent upon ATP-driven events.
However, due to the brittle and fragile properties of the polyethersulfone fiber, making it difficult to use with a U-shaped cannula design, we used hemophane probes for our in vivo experiments.
An extended treatment time of 30 min revealed a significant increase in fluorine content; however, the 30-min treatment time appeared to negatively alter the physical properties of the membrane making it fragile and discolored.
However, silk is one of the natural fibres most sensitive to environmental degradation factors that cause deterioration of its intrinsic properties, becoming fragile and therefore difficult to preserve.
However, several analyses suggest that rearrangement breakpoints and repeat sequences (flanking regions of segmental duplications) share similar physicochemical properties (high DNA flexibility and low stability) characteristic of fragile sites [ 1, 8].
The organisation believes that tools such as Google's Trekker technology are valuable, particularly in terms of sustainable tourism, by documenting properties too fragile to be opened to the wider public.
Although the observation that the RNA-binding properties of the KH2 domain of the Fragile X paralogs have been conserved during evolution is important, these data additionally suggest that the use of dfmr1-null Drosophila as a disease model for Fragile X syndrome is likely to be fruitful, as RNA binding by this family may have been largely conserved through evolution.
Durable edifices are rarely, at least in the West, constructed of fragile materials, but "hard" and "soft" are no longer the defining properties of either architecture or fashion.
