Sentence examples for proper imprint from inspiring English sources

During development, all diploid somatic cells have a proper imprint imposed on chromosomes inherited from both of the parents, except precursors of gametes (primordial germ cells) that erase imprinting during their developmental migration to the genital ridges [ 12].

Failure to establish a proper imprint of this region in humans has been already described to result in the neurobehavioral disorders, Prader-Willi syndrome (PWS) and Angelman syndrome (AS) [ 40]; however, this is the first time that an association with cancer is established.

One such NFI-bound boundary coincides with a regulatory region required for the proper imprinting of the Blcat and Nnat genomic locus, where two overlapping genes are differentially expressed and imprinted during murine and human development [ 47].

The proper imprinting of paternal and maternal genes, which are combined in the zygote at the time of fertilization, is required for balanced expression ("dosage") and to initiate embryogenesis.

Proper imprinted gene expression is essential for mammalian development and its misregulation plays major roles in several human diseases, including many types of cancers and Beckwith-Wiedemann, Silver-Russell, Angelman, and Prader-Willi syndromes (Butler 2009; Barlow 2011; Ferguson-Smith 2011; Garfield et al. 2011; Lee and Bartolomei 2013).

It's been so long since comic fans have gotten a proper new imprint from a major publisher, and so far Young Animal seems perfectly clued into everything that makes alternative comics amazing: weirdness, risk taking, and damn good art.

But whereas Rasgrf1 imprinted expression depends only on the paternal repeats [32], proper AK029869 imprinting depended on both parental repeats.

Because VEZF1 and USF barrier proteins were dispensable for insulation at the ICR position, chromatin barrier formation in the maternal allele may not be required at all for proper regulation of imprinted genes at the ICR position.

Proper regulation of imprinted genes is required for normal growth and development in mammals.

Because SCNT embryo requires a proper expression of imprinting genes for normal development (Okae et al. 2014; Suzuki et al. 2011), we inquired into imprinting genes.

In vitro culture may expose the genome to environmental factors that prevent the proper establishment of the imprint.