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This is a 3D map that shows the most critical residues in the protein structure to proper folding.
Similar to other members in the family, BiP plays a central role in the proper folding and assembly of proteins.
Proper folding of all proteins was analyzed by 2D 1H, 15N-TROSY NMR experiments.
Hence, sfGFP also imparts solubility and enables proper folding of poorly folding fusion proteins [ 12, 15].
Hsc70 and DNAJA1 are known to function together to promote proper folding of proteins (Meacham et al., 1999).
As with a parachute, proper folding is critical.
A critical consideration for this strategy is that the structured nucleic acid modules retain proper folding within the delivery platform.
We find that TRiC's binding to CSA ensures its proper folding and DDB1-dependent assembly into the CRLCSA complex.
For the proper folding of the triple helix collagens contain trimerization domains.
Recent years have witnessed a steady stream of reports that describe other proteins that require TRiC for proper folding.
Here it functions to promote proper folding of proteins, particularly in highly stressed cells.
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