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Nurses helped with questionnaire completion where necessary, conducted short interviews and undertook physical measurements.
Where necessary for completion of missing data, we contacted the parents and caregivers of the patients.
Proper allele detection was checked manually and adjusted where necessary.
Altogether these data indicated that during mitosis HG-EOC cells expressing p53MUT accumulate a significantly higher amount of damaged DNA and that, in this setting, stathmin expression is necessary for the proper completion of M phase.
A factor further contributing to sterility is the observation that chromosome pairing has been found to be a necessary step for the proper completion of meiosis, at least in eutherian mammals (C&O p 262-264, citing Searle1993).
"His doctors in Bagram suggested that he needed to be treated in a proper hospital where all necessary facilities and resources are available," Mr. Tahiri said.
After completion of data collection, the data were reviewed for inconsistencies and where necessary, corrections were made after contacting the respondents before data entry and analysis were done.
Outstanding queries regarding the completion of the CRF will be undertaken with each participating centre where necessary to ensure accuracy of data.
These consisted of three patient and two GP questionnaires: This was a short preliminary questionnaire for self-completion by the patient with assistance from the research assistant where necessary.
A proper failure regime needs to be put in place, including rapid replacement of sponsors and leadership where necessary.
Concede where necessary!
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com