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Obesity leads to an increased propensity for the development of a complex array of factors that increase the risk to develop cardiovascular disease or type 2 diabetes, which have been termed the metabolic syndrome (abdominal obesity, atherogenic dyslipidemia, hypertension, and insulin resistance) [ 11].
As a result, many patients tend to over-rely on short-acting β-2 agonist medications for quick relief of symptoms at the expense of omitting their ICS therapy, thus lowering anti-inflammatory protection and increasing the propensity for the development of severe and potentially life-threatening exacerbations [17].
At the extreme, these normal population variances could also contribute to propensity for the development of chronic inflammatory and infectious diseases.
Affected patients are uniquely susceptible to recurrent infection with encapsulated organisms and have an increased propensity for the development of inflammatory and autoimmune manifestations.
82 Betel nut chewing is a major risk factor for health, with the propensity for the development of malignancies of the gastrointestinal tract.
The most parsimonious explanation would be that a propensity for the development of telangiectasiae and CVD are part of a common biological pathway on the basis of a genetically predisposed endothelium.
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In addition to symptoms directly related to the hand itself, it is also related to osteoarthritis at other sites and there is evidence that the presence of HOA increases the propensity for the development and progression of both knee and hip osteoarthritis (OA) [ 4].
We discuss these findings with reference to the placement of critical sequence residues within the polypeptide chain, the design of polypeptides with lower amyloid formation propensities and the development of aggregation inhibitors as potential therapeutics for protein depositional disorders.
Previous studies have shown that hyperoxaluria is concomitant with the formation of CaOx crystals and the subsequent propensity of these crystals towards renal cells greatly increases the risk for the development of urolithiasis.
"All things being equal, if a child is born with a slightly diminished propensity to take pleasure in social interactions, this might lead to drastic consequences for the development of social skills down the line," Chevallier said.
Certain antimicrobial classes that are broad-spectrum and have a propensity for killing colonic bacteria, especially cephalosporins, clindamycin, and most recently, fluoroquinolones, may pose a greater risk for the development of the disease.
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Justyna Jupowicz-Kozak
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