For the case of single node interventions, the model recapitulates the known resistance mechanisms to PI3K inhibitors: PIM, SGK1, mTORC1 (mTORC1 = ON, TSC = OFF, PRAS40 = OFF, or translation = ON), and HER2/HER3 (HER2/HER3 = 2), which lead to a decrease in the apoptosis propensity and increase in the proliferation propensity.
The MOR is the median odds ratio between the patient in the hospital with higher mortality propensity and the patient in the hospital with lower mortality propensity.
Our study models controlled for age both through the use of propensity scores and in the actual model.
Our aim is to deliver more comprehensive and precise annotations of the crystallization propensity (and the other steps in the crystallization process).
The theory aims to explain why crime occurs by investigating the characteristics of these individuals (particularly their crime propensity) and the features of the environments in which they take part (e.g., Wikström [2014]).
Since the interacting pairs demonstrate stronger propensity to be regulated by sc-miRNAs than non-interacting pairs, we next asked whether there are some correlation between the propensity and the distance between two proteins in the network.
We suggest that the lower overall mating propensity and the phenotypic plasticity in response to sex ratio have evolved in the novel stonewort ecotype following invasion of the novel habitat.
As we simultaneously included comorbidities, social characteristics, CCI and propensity score in the multivariate regression model, a potential numerical problem concerned multicollinearity between covariates, which might render estimated regression coefficients invalid.
The presence of this program was therefore included within the possible bias factors considered in the propensity score analysis and in the multivariable analysis.
Aβ42 has a higher aggregation propensity and is the primary isoform found in AD-associated amyloid plaques.
