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(d) Velocity profiles (colour) along the propagation pathway without (left) and with (right) synaptic antagonists.
Based on HAZOP analysis results, hazard scenario models are built to explicitly represent the propagation pathway of faults.
It can diagnose the root cause of the process fault precisely as well as identify the fault propagation pathway.
In this article, a novel dynamic Bayesian network based networked process monitoring approach is proposed for fault detection, propagation pathway identification and root cause diagnosis.
The fault root cause was traced by analyzing the changes in information transfer between the nodes along with the fault propagation pathway.
To support the development of pharmaceuticals using the Quality by Design approach, we develop a system to analyze the scenarios in which manufacturing failures can affect product quality via complex propagation pathway.
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Our study focused on neurites that were depolarized by extracellular electrical stimulation, which showed propagation pathways between stimulation sites and the soma.
Therefore, in order to ensure that velocity measurements characterized axonal signals and did not include dendritic spikes, we only analysed propagation pathways identified between a successfully tested stimulation site and subsequently evoked soma.
Subsequent crack propagation pathways follow inherent topographical features in the tissue and lengthen with increased tissue hydration.
We propose a system, Quality-HAZOP, to analyze the scenarios in which manufacturing errors can affect product quality via complex propagation pathways.
Mapping of trigger sites and/or propagation pathways for soman-induced seizures may provide clues for the designing of anticonvulsant drugs.
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