Exact(8)
Direct numerical simulations are performed of flames that develop into steadily and stably propagating cells.
However, consistent with the functional similarity of these populations, expression signatures characteristic of leukaemia propagating cells in acute myeloid leukaemia fail to distinguish between the different populations.
SOX2+ tumor propagating cells have recently been shown to drive cell growth specifically in SHH MB mouse tumors (Ahlfeld et al., 2013; Vanner et al., 2014).
RESULTS: Here, we show that propagating cells in acute lymphoblastic leukaemia cannot be enriched by purification based on a range of B-cell maturation markers.
Antibiotics were used in the growth medium of THP-1 cells to avoid contamination of the propagating cells.
To address the functional role of SVZ tumor cell populations, we characterised matched T- and SVZ-tumor propagating cells i n vitro and in vivo.
Similar(52)
The cancer stem-tumor-propagating cells concept, with only a fraction of the cancer cells being competitive, implies the same conclusion [ 132].
The other, more competitive cells may correspond to the so-called cancer stem cells postulated by the cancer stem cell theory that we called cancer stem tumor-propagating cellstem tumor-propagating
We identified a population of long-term tumor-propagating cells (TPCs) in a mouse model of SCLC.
This interpretation embodies the implicit assumption that cancer stem cells or tumor-propagating cells are themselves genetically and functionally diverse.
Additionally, a YAP/TAZ gene expression signature is significantly associated with tumor-propagating cells and human lung cancer progression (Lau et al., 2014).
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