Proof-of-concept examples are used to demonstrate the tools.
Using several proof-of-concept examples, we demonstrate that I-optimal designs offer both flexibility and small variances of prediction.
Finally, a universal joint and a Bennett linkage fabricated by DNA origami self-assembly are chosen as proof-of-concept examples to verify the feasibility of projection kinematic analysis of DOM.
It is very important to note that these experiments are just preliminary proof-of-concept examples to test the abilities of the system and introduce a new method of microscopy.
Figure 7 presents proof-of-concept examples of flaps and lenticules.
In further research, there will be more key biochemical systems to be used as proof-of-concept examples.
Theoretical analysis, proof-of-concept examples, and experimental studies demonstrate the ability of our mining approach to identify bistable genes by sampling across a variety of different conditions.
Proof-of-concept examples have been described where PROTACs were used to degrade the estrogen- and androgen-receptor, methionine aminopeptidase-2, as well as the aryl hydrocarbon receptor.
Proof-of-concept examples of similar devices have recently been introduced, including engineered Escherichia coli that can sense and kill Pseudomonas aeruginosa biofilms by eavesdropping on the target quorum sensing signals and releasing antibiotic pyocin proteins in response [ 45].
These proof-of-concept examples demonstrate the great potential for using biological logic circuits to customize cell sensing and signalling for many useful applications (Khalil and Collins, 2010; Wang and Buck, 2012; Weber and Fussenegger, 2012).
The approach may be useful for pure structure alignment, but its performance needs to be demonstrated quantitatively in terms of accuracy and speed, rather than by the proof-of-concept examples given here.
