Fit-for-purpose validation provides biomarker researchers with an approach that tailors the burden and stringency of proof required to validate an assay to take account of both the nature of technology utilised and the context in which the biomarker will be applied.
The current prototype was developed as a proof of concept to validate the design kinematics.
The vehicle designs are developed for proof of concept, to validate mission approaches and understand the value of new technologies.
Note that the current prototype was developed as a proof of concept to validate the design kinematics and uses low-cost brushed DC motors and gear boxes with limited bandwidth, which are the cause of the observed time delay.
The experiments were performed for two major reasons: First of all as a proof of concept to validate the bioassay with yet untested inhibitors.
It is an entirely human craving to have proof we were there, and to validate that proof with endless witnesses in the form of friends or followers.
As a proof of concept and to validate the antigen, we analyzed serum, whole blood and milk samples obtained from non-infected, experimentally infected and vaccinated animals included in a vaccination/infection trial performed in our laboratory as well as more than 1000 serum and milk samples obtained from naturally infected and S19-vaccinated animals from Argentina.
Therefore, we first provide a proof of concept application to validate our approach, where we apply the proposed temporal and spatiotemporal classifiers to fNIRS data obtained during a visual checkerboard task and then assess whether the resulting accuracies are higher over the primary visual cortex than over adjacent areas.
We present proof-of-concept devices to validate the suitability of high-resolution stereolithography fabrication, polymer material properties, and increased design freedom for realizing 3D phononic crystals.
We present two proof-of-principle experiments to validate our approach.
