For "a-proof-of-concept" purpose, anti-CD34 antibody was used in the current experiments.
In the present study, for proof-of-concept purpose, the RNA replicase encoding plasmid was dosed to mice by subcutaneous peritumoral injection.
An extensive numerical analysis has been carried out for proof-of-concept purposes.
For proof-of-principle purposes, silicon substrates were functionalized with the GO MIPs and sensing was performed on histamine in buffer solutions.
The MR scan was acquired using the Golden Angle Radial Sparse Parallel (GRASP) sequence [1], simultaneously with a 5 minute PET scan, while the patient was asked to move his head repetitively from side to side for proof-of-principle purposes.
For proof-of-concept purposes we compared the unfolding and refolding dynamics of a previously studied stable 20 base-pair (bp) long DNA hairpin 13 using conventional dsDNA linkers versus using stiff ten-helix bundle linkers.
The literature shows many prototypes developed and built both with proof of principle purposes and with performance oriented purposes.
A 6-well version was used for proof of concept purposes; however, the strategy can be easily expanded to higher density multiwell plates (e.g. 12, 24, 48 or 96-wells) as shown in figure 1b.
The SelSim model assumes the initial mutation to be rare [24], and may overestimate the selection signal if selection started on a mutation that reached significant frequency [43].Our study used SelSim for "proof of principle" purposes to demonstrate the patterns of our measurements: a decrease in heterozygosity, and particularly the increase in the S2FST measure we described.
For proof of principle purposes, the BLAST database that we used was built only with the two set of 454-derived unigenes, as if no other information for this species was available.
