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However Walcott had exhibited proof of progression before damaging his knee – his movement had grown shrewder, his passing more deliberate and his finishing far less forgiving – and against Brighton it did not take long for the 25-year-old to re-assert his value to Arsenal.
Because intermediate scans to determine the exact timing of progression were not performed, and arterial disease improved or stabilized at subsequent angiography, we had no proof of progression beyond 6 months, and therefore classified the course of arteriopathy as TCA in these three patients.
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Most open-source projects are living proof of this progression.
Definitive proof of the progression to invasive disease will require the discovery of identical breakpoints in adjacent lesions using array-CGH technology.
The study will exclude men suitable for curative treatment, but who choose to be monitored until proof of further progression (active surveillance).
The particular parameters for this objective are: Evidence for anti-tumor activity of the IMP in subjects with recurrent GBM (Proof of Concept, PoC), Progression-free Survival (PFS) up to 6 months after study inclusion, Overall survival (OS) up to 6 months after study inclusion.
Furthermore, the fact that isolated examples of empowerment 'successes' exist (i.e. interventions meeting stage two or three) demonstrates proof of concept for the progression of FSW community empowerment in African settings.
Secondary objectives are proof of concept (PoC) and Progression-free Survival (PFS) up to 6 months.
Indeed, proof-of-principle experiments show that inhibition of HIF-1α delays APL progression and prolong survival of leukemic mice.
Efficacy endpoints of this proof-of-concept study included response rate, time to first metastasis, progression-free and overall survival (OS).
Pre-defined efficacy endpoints for this proof-of-concept study included objective response rate, time to first metastasis, progression-free survival (PFS) and overall survival (OS).
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