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For example, proof of principle experimental data reveal that intelligent targeting of induced signalling alongside the primary therapy can achieve a previously unobtainable level of cancer cell kill and substantially improve anti-tumour response [ 76].
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Proof-of-principle experimental results of biomolecular interaction analysis with functionalized fiber-tip resonators are presented.
Proof-of-principle experimental studies utilizing knockin mice have also demonstrated that transgenic overexpression of the cardiac creatine transporter or the muscle CK isoform CKM can elicit marked protection against stress-induced heart injury.
Our results also provide a proof-of-principle experimental model to understand how such a phenomenon could be possible also in human patients.
Rationale for the experiment Preliminary data/proof of principle Experimental approaches and their alternatives Reconfiguring/jettisoning an aim Data interpretation.
Proof-of-principle simulation and experimental works have demonstrated this method is practical.
Including inhibition from SOMs to PVs in the proof-of-principle model supported experimental findings.
So far, the majority of reports in this area have been proof-of-principle studies in experimental models, although there have been some recent reports on the effect of early life environment on epigenetic processes in humans.
The proof-of principle experiment of the BPL method has been described in detail [ 18].
As explained above, the model was constructed as a proof-of-principle for understanding our experimental findings, rather than with the goal of replicating a detailed biological network.
46, 4212 4220] and in this work, packed bed chemical-looping combustion was investigated experimentally to provide an experimental proof-of-principle.
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