Sentence examples for proof of essential from inspiring English sources

In children's entertainment, especially bad children's entertainment, imperfections are presented as proof of essential goodness.

Having felt for years that the great man's reputation was under stealth assault from those never inclined to see any pedagogical virtue behind the tough love and bluster of football culture, they pointed to the library that bore his name, as though proof of his essential goodness were exculpatory.

As a proof of concept, essential genes were predicted by both local (Clustering coefficient) and global (Closeness centrality) centrality measures using the minimum error criteria in each case.

The rigorous proofs of the essential features of the multicolor lattice gas are facilitated by use of an equivalent "subparticle" representation in which the color is represented by underlying two-state "spins".

It is found that a reliable method of measuring any pharmacokinetic or pharmacodynamic end point used in phase I or proof-of-concept studies is essential to proper interpretation of the results.

Within the field of molecular farming these techniques are essential for proof-of-concept studies prior to the establishment of production lines.

Quantitative analysis of drug target interactions in tumour biopsies before and after treatment is essential for early proof-of-concept validation, especially during Phase I/II studies.

Apart from genetic mouse models, pharmacological agents are essential to provide proof-of-principle in non-mouse species and to serve as experimental therapeutics.

Compelling pre-clinical animal data will be essential to provide proof-of-concept and to justify any clinical attempt to boost Treg cells in women.

The proof of this fact makes essential use of the continuity axioms discussed above and thereby shows how classical mathematics can guide the search for intuitionistic analogues that, however, have to be proved in a completely different way, sometimes using principles unacceptable from a classical point of view.

In view of the therapeutic promise of upregulation of CSPα and the undesired consequences of CSPα dysfunction, our data establish an essential proof of principle that pharmaceutical agents can selectively target the neuroprotective J protein CSPα.