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The concept of ultraprotective mechanical ventilation was tested in a proof-of concept trial, with CO2 removal performed by a modified veno-venous hemofiltration platform.
These initial, proof-of-concept trials will be conducted using the patients' own cells.
Clinical proof-of-concept trials crucially inform major resource deployment decisions.
And it has several other clients that are in proof-of-concept trials that are looking to move to full deployments of the software.
Current funding for smart city initiatives is only good enough for proof-of-concept trials, which would lead, at best, to a piecemeal approach to smart city construction.
Gault transferred to a new research area -- Alzheimer's disease -- where she is now responsible for several proof-of-concept trials, also known as phase II clinical trials.
However, challenges remain in designing optimal proof-of-concept trials for the clinical development of compounds targeting the elimination of CSCs.
Proof-of-concept trials in non-human primates and in one human efficacy trial have provided scientific clues for a vaccine that could provide broad and durable protection against HIV.
A more complete preclinical evaluation of these questions will ultimately allow educated proof-of-concept trials to test the efficacy of selective 5-HT2CR asonists adjunctiveive therapy in chronic health maladies including obesity, eating disorders and drug addiction.
Recent proof-of-concept trials have examined the impact of anti-herpetic therapy on HIV-1 viral load in plasma and/or genital secretions [12] [12] [12].
Several proof-of-concept trials have shown that HSV-2 suppression with daily acyclovir or valacyclovir in HIV-1/HSV-2 co-infected pereduceseduces HIV-1 RNA by 0.26 0.53 log10 and cervical or rectal HIV-1 RNA by 0.16 0.35 log10 [40] [41], [42], [43], [43].
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