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Hence, we conducted proof of concept laboratory studies using DADS in a chondrosarcoma cell line, measuring both cellular acetylation and its ability to repress the IL-1/OSM-induced expression of key matrix-degrading metalloproteinases as a surrogate for the destruction/protection of articular cartilage.
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Nonradioactive strontium was used for the proof-of-concept laboratory experiments.
As a proof of concept, our laboratory was able to show, at least in a mouse model, the ability to roughly define risk groups in mice using salivary gland protein profiles [ 88].
Proof-of concept experimental results are provided.
The mobile potentiostat has been evaluated in the laboratory with a set of proof-of-concept experiments, and its analytical performance compared with a commercial laboratory potentiostat (R2=0.9999).
The design of the VeriTainer system and results from both the laboratory and a proof-of-concept test at the Port of Oakland, California will be presented.
In part because of the challenges around the use of the SLEDAI or the BILAG in clinical trials, pharmaceutical companies have focused phase II proof-of-concept clinical trials on lupus nephritis, where laboratory measurements of proteinuria or the glomerular filtration rate provide objective measurements of renal disease.
Our laboratory provided the first proof-of-concept that double-stranded short interfering RNA (ds-siRNA) can act as potent and specific antiviral agents.
The VA system used in this study was a laboratory system sufficient for proof-of-concept examinations and exploration of the potential of VA in breast imaging.
Laboratory tests with contaminated sediment show proof-of-concept through reductions in HOC bioavailability.
As a proof-of-concept experiment, millistructured equipment was designed, manufactured and tested at a laboratory scale.
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