In silico and experimental proof-of-concept cases have shown that AlignMiner can be successfully used to designing specific polymerase chain reaction primers as well as potential epitopes for antibodies.
This paper presents a formal description and a prototypical implementation of our approach with a proof-of-concept case study.
Joint tephrochronological/archaeological research in historic periods has the potential to provide key proof-of-concept case studies for this emerging field.
We develop and demonstrate through a proof-of-concept case study, a new "query-driven" heuristics for database design that seeks to identify database structures that perform robustly in dynamic settings with dynamic queries.
The proof-of-concept case study demonstrates the use of the Navigation Guide to efficiently apply the rigor and transparency of systematic review methodology to environmental health questions.
The benefits of such approach are discussed and a subsystem of the proposed architecture is implemented in FPGA technology as a proof of concept case study.
We present a proof of concept case study in which SEP is used to enable a 700 kg Explorer-class observatory payload to reach an orbit beyond where the zodiacal dust limits observatory sensitivity.
This research tests the clinical applicability of a newly improved computer-based method for the proof of concept case of tracking changes in important hemodynamic indices due to the influence acute pulmonary embolism (APE).
The model derivations and reformulations to cluster-based models are presented and the usage highlighted through a simple proof of concept example and a case study.
The prototype architecture used in our proof-of-concept use-case scenario involves real-time monitoring of service performance by an Autonomic Manager.
We utilized colorectal cancer (CRC) as a proof-of-concept use case to illustrate the approach.
