Therefore, we propose a combination of electrochemotherapy with peritumoral IL-12 electrotransfer, as a proof of principle, using electrochemotherapy boosted with immunogene electrotransfer as in situ vaccination for successful tumor treatment.
These results provide the proof-of-principle that engineered exosomes can boost the CD8+ T cell immunity in HCV-infected patients, thus representing a suitable option for patients resisting the therapies with recently discovered HCV inhibitors.
Mr. Branson showed a successful "proof of concept" that might have boosted the confidence of consumers, industry, policy makers and investors and catalyzed more biofuel research.
Measurements of mesoscale proof-of-concept devices indicate an inductance boost of up to three orders of magnitude compared to static electrical devices, with maximum inductive quality factor up to 7.4.
Compelling pre-clinical animal data will be essential to provide proof-of-concept and to justify any clinical attempt to boost Treg cells in women.
A proof-of-principle study, published in Nature, showed that human embryonic stem cells boosted heart regeneration when transplanted into injured macaque hearts.
Further proof of their power?
Here, we propose a model, a combination of electrochemotherapy with immunostimulating peritumoral IL-12 electrotransfer, as a proof of principle that electrochemotherapy can be used as in situ vaccination boosted with immunogene electrotransfer (Fig. 3).
These results provide a proof of concept that a distally related retroviral SIV Env protein boost can increase pre-existing NAb responses against HIV-1.
If authors wish to traditionally publish, proof of a successful campaign on Pubslush will be a huge boost to an author's query letter.
Well before that, however, it's a proof of concept that the brain's neural codes can be identified, recorded and hacked to boost memory.
