Sentence examples for proof of activity from inspiring English sources

Interestingly the company is looking at the blockchain to register "proof of activity" for invoice payments, purchase orders, and the like.

The first clinical study was designed to provide proof of activity that CC-930 inhibits JNK in healthy volunteers and to select doses for evaluation in IPF patients.

Clinical studies of HAdV-5-based gene therapy vectors, vaccines, and oncolytic viruses have shown safety and proof of activity in patients, but they also revealed critical roadblocks to therapeutic efficacy.

Interestingly, the effectiveness of DNA vaccines in small animals has not translated to primates and humans and proof of activity in clinical trials has only recently been reported.

Dose selection and proof of activity are often based on a surrogate endpoint (such as a biomarker) for which a study with small sample sizes can have insufficient power.

This study was a small signal seeking proof-of-activity study and was not powered to demonstrate statistically significant differences between treatment groups.

We conducted a proof-of-activity study using allergen inhalation challenge in mild atopic asthmatic subjects to evaluate the effects of blocking anti-OX40L on allergen-induced airway responses.

This study was a small proof-of-activity study to demonstrate the pharmacological activity of lebrikizumab and to explore the feasibility of IL13-related biomarkers as predictive biomarkers for response.

This study also illustrates how allergen challenge proof-of-activity studies can be used to explore mechanistic activity of novel therapeutics prior to exposing a large number of patients to experimental therapies.

We were able to provide a high exposure of antibody in this small proof-of-activity study based on safety exposures in humans but the exposures in the non-human primate studies were at approximately twofold to threefold higher than given in this study [6].

For proof-of-principle, activity of 8-MeXAA, 7,8-MeXAA and DMXAA was measured against A375 human melanoma xenografts.