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Of the 102 suspected TB patients initially enrolled, 13 were rejected for absence of formal proof of active TB as defined by these criteria.
Distortion products, however, may be produced even in the absence of active amplification [ 21] and on their own do not constitute unambiguous proof of active amplification.
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None of this adds up to absolute proof of his active role as a cultural arbiter.
This would provide the proof of concept of active delivery vehicles able to guide their movement towards diseased cells.
The study will exclude men suitable for curative treatment, but who choose to be monitored until proof of further progression (active surveillance).
Combined with the recommendations of previous studies, IgG anti-PT titers ≥ 100 IU/mL detected in a single serum sample were a diagnostic proof of recent or active B.pertussis infection, if the subject has not received a booster dose of pertussis vaccine within the previous one year [ 17, 18].
To verify the effectiveness of the proposed technique, two proof-of-concept double-balanced down-conversion active mixers have been designed and fabricated in 0.13-µm CMOS.
The canakinumab doses were selected based on the results of a previous dose-escalation, proof-of-concept study in patients with active RA despite maximum tolerated doses of methotrexate, as well as on pharmacokinetic/pharmacodynamic modeling [ 10].
The present proof-of-concept study examines the potential to incorporate active tremor compensation into an active tool tip, in this case a micro-forceps.
Their treatment in proof-net-like proof systems is currently a topic of active research.
To foster the necessary shift to a pro-active systems medicine, proof-of-concept studies are needed.
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