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The obtained result provided strong proof for the role of STAT5b in invasion (Fig. 4c).
Additional proof for the role of LLD in LBP would be provided by a randomised controlled trial showing a beneficial effect of LLD correction on LBP symptoms.
As an additional proof for the role of PPARα in acute phase response, fenofibrate treated hyperlipidemic patients were shown to have decreased plasma concentration of fibrinogen, C-reactive protein, serum amyloid A, plasminogen and a2 macroglobulin [146].
Additional proof for the role of PAR-1 in melanoma dissemination is the fact that it is highly expressed both in metastatic melanoma cell lines and in metastatic lesions in comparison to primary nevi and normal skin [ 21, 250].
As a final proof for the role of Rack1 in autophagy, we have generated transgenic animals expressing Rack1 with a C-terminal FLAG-HA tag by using a DNA construct from the ongoing Drosophila proteomics project.
Functional proof for the role of this amino acid alteration in the phenotype determination was obtained by site directed mutagenesis followed by transgenic expression in Arabidopsis callus system [ 15].
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However, no definitive proof was provided for the role of IL-8 in intratumoral retention of DC [1].
Pilot study results with a prototype video game tentatively support theory-based predictions regarding the role of dynamic gestures for fostering insight and proof-with-insight, and for the role of action coupled with language to promote proof-with-insight.
This experiment provided the crucial proof for the indispensable role of PLA2 activity in the reduction of endocytosis by AtxA in yeast.
Ultimate proof for the essential role of ATGL as TG lipase in vivo came from the enlightening phenotype of ATGL-knockout mice (Haemmerle et al, 2006).
Best proof for the critical role of bone-marrow derived alveolar macrophages for surfactant homeostasis is provided by the correction of PAP by SCT.
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