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To a lesser extent, also mutations V182T and I180T drastically reduced EGFP induction upon 2-HBP addition – mostly after 2 h, but after 4 h induction time the difference to the wild-type was less pronounced (type II, Table 1, Fig. 3).
Individuals with a pronounced type A behaviour, also referred to as coronary prone behaviour, are possibly more prone to injury [ 27].
Canal development was most pronounced (Type 1; Figure 2) in samples from the downstream Tarawera (83%) and the Rangitaiki River (67%) samples (Table 2).
There are two interesting new findings: a pronounced type of asymmetry in the PCH-2 (TRIP13 homolog) AAA+ ATPase – two of the subunits in the hexametric arrangement are bound to sulfate, two are apparently apo, and two are bound to ADP, resulting in large conformational differences between the "small" subdomain of the AAA+ module.
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A biphasic increase in serum cortisol was also observed at Weeks 2 and 5. Histopathology showed that muscle lesions were mainly composed of degeneration and atrophy of the muscle fibers, and ATPase staining revealed that the changes were more pronounced in type II muscle fiber than type I muscle fiber.
Although all types of muscle fibers are larger in men, the sex difference is especially pronounced in type 2 fibers so that there is a greater ratio of type 2 fiber mass to type 1 fiber mass in men [1], [5], [10].
Distribution of marker types among the linkage groups showed pronounced marker type bias in LG5, 6, 9, and 10.
RESULTS Recognition of a type 1 diabetes specific GAD65Ab epitope was more pronounced in type 1 diabetic patients than in nonprogressed (P < 0.001) or progressed (P < 0.01) LADA patients, with no significant differences between the two LADA cohorts.
All patients showed muscle fibre atrophy, which was more pronounced in type II fibres, and great fibre size diversity; the mean area of type II fibres was 4,654 ± 2,626 μm, a 18 43% reduction when compared to previous reports on healthy subjects of similar age (Table 1).
It is unknown if differences in growth rates exist between type A clades (A1a, A1b and A2) or between type A clades and type B. In addition to type B infected mice having higher bacterial burdens, organs were larger in type B infected mice, indicative of a strong inflammatory response that is not as pronounced in type A infected mice.
During gestation, the increase in serum lipid concentrations was less pronounced in type 2 diabetic subjects.
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