Sentence examples for pronounced side effects from inspiring English sources

On the other hand, evolving toxic products from the hydrolysis process might lead to the more pronounced side effects observed with complex 1.

However, this may be associated with more pronounced side effects, especially concerning the salivary glands.

However high concentrations of these agents are required for this purpose and thus lead to pronounced side effects; thus the development of 2nd generation chemosensitizers was prompted.

The use of rFVIIa in patients with DIC – where there is systemic activation of coagulation with systemic exposure of tissue factor [ 15] – could lead to more pronounced side effects.

Latest reports support effective analgesia, especially in severe pain, where opiates play a more prominent role, particularly with controlled-release formulations of morphine, oxycodone, and transdermal patches of fentanyl and buprenorphine, which have less pronounced side effects.

However, this treatment approach also showed limited overall survival and was accompanied by pronounced toxic side effects (Baghi et al, 2006; Vermorken and Specenier, 2010; Tselis et al, 2011).

The beta-adrenergic blockers may be associated with pronounced systemic side effects in some patients, including worsening of reactive airway disease and aggravation of cardiac conduction disease [ 46, 53, 54].

While more recently introduced basal insulin analogs demonstrate less variability than NPH, leading to a reduced risk of hypoglycemia [ 30] and a greater potential for patients to confidently self-titrate [ 45], there is still a pronounced fear of these side effects among patients [ 39, 40].

The in vivo anticancer experiment further revealed the pronounced anticancer effects and the lower side effects of the HFNDs.

In light of the finding that MKL1 knockout mice are viable and fertile, and only fail to nurse their offspring (Li et al, 2006; Sun et al, 2006), we anticipate that a prolonged treatment may not lead to pronounced unwanted side-effects related to other functions of MKL1.

The combination treatment showed more effective suppression of tumor growth than those with single agent alone, being associated with pronounced intratumoral T-lymphocyte infiltration and minor side effects.