Sentence examples for pronounced instability from inspiring English sources

While the faithful transmission of genetic information requires a fidelity and stability of DNA that is involved in translation into proteins, it has become evident that a large part of noncoding DNA is organized in repeated sequences, which often exhibit a pronounced instability and dynamics.

Following these lines of arguments, rapid depletion of an enzyme from the cells upon passage from one developmental stage to the other, as observed for Pfk, therefore requires an active degradation mechanism or must rely on a pronounced instability of the protein.

Results: Patients showing neglect displayed pronounced postural instability compared with other patients and controls.

G9a-depleted tumours develop after a prolonged latency compared with their wild-type counterparts, but are more aggressive and have an expanded cancer progenitor pool, pronounced genomic instability and frequent loss-of-function p53 mutations.

Most affected individuals also have cognitive (intellectual) impairment and psychiatric symptoms such as anxiety, paranoia, depression, obsessive behavior, and pronounced emotional instability.

As well, cells from MMTV-PyMT; NEDD9-null mammary tumours exhibit pronounced genomic instability, which ultimately facilitates the selection of cells with a more aggressive phenotype [ 27].

It is found that in contrast to the non-reactive system, the reactive polymer blends display pronounced hydrodynamic instabilities followed by the formation of branched fingers.

We offer this phenomenon as an explanation for the lateral instability and pronounced planation activity of semi-arid channels, especially on gently sloping piedmont surfaces.

When the resulting instability becomes sufficiently pronounced, the crystal transforms co-operatively to one of the two possible lower symmetry states with equivalent structures.

Moreover, we observed that thermal instability was most pronounced in variants mapping to the β-sheet domain of the protein (Y133H, R181C) or to the loop interconnecting this domain and the C-terminal α-helix domain (D241G).

It is not clear how pronounced the effects of a modulational instability are expected to be at this intermediate spatial scale.