CYCLIN A is expressed in late G1, demonstrates pronounced expression during S-phase, and increases as the cells advance towards G2, with degradation in early mitosis; B type cyclins begin to be expressed in late S-phase, and drive the cells though G2- and M- phases of the cell cycle [30].
Although its effect was less pronounced, expression of the MERS-CoV PLpro-TM also caused substantial increase in LC3-II expression (lane 4, Fig. 3A).
Consistent with increased PL activity, we have detected pronounced expression levels of annexin II on both the cell surface of PBMC and in lesional skin from patients with psoriasis.
The largest constitutive exon of number 2 of ACHE (Figure 6A,C) showed pronounced expression compared to the other ACHE exons in exon array data sets from cerebellum, breast, liver, muscle, kidney, heart, pancreas and both normal and tumor colons (Figure 6A, gene structure under 6B).
Moss MIR159/319 genes have pronounced expression in sp2 and sp4 miRNAs.
A large number (~100) of miRNAs had pronounced expression in placenta compared to most of the other tissues.
Thus, male P. taeniatus may get both direct as well as indirect benefits when choosing females that show pronounced expression of the quality signal.
MTUS1/ATIP was pronounced expression in normal salivary gland tissues, but decreased expression in SACC samples from patients with or without lung metastasis.
In addition, pronounced expression of NMU mRNA is observed in the pars tuberalis of the pituitary, a structure that surrounds the hypophysial stalk (16), suggesting that NMU may be involved in hypothalamic-pituitary communication.
Instead, pronounced expression of some nucleobase and phosphorus transporters was demonstrated in phloem vessels [ 39, 40] suggesting that some additional reaction(s) must lead to further degradation of the S1 type nuclease derived DNA fragments and subsequent nucleotide catabolism.
We observed increased expression of P-gp protein in the cell line resistant to paclitaxel, pronounced expression in the cell lines resistant to doxorubicin and some expression in the cell line resistant to vincristine; we observed a very high correlation between transcript and protein levels.
