Sentence examples for prone to unfold from inspiring English sources
As a consequence, large amounts of monomers originate that are prone to unfold rapidly into a cross beta-sheet configuration. 2 These misfolded, beta-rich monomers, in turn, have a strong tendency for self-aggregation, leading to the formation of nonfibrillar oligomers, protofibrils, and fibrils.
Of the three mutants that lack an AQN intrinsic salt bridge, D212N was more prone to unfolding at 80°C than the wild-type enzyme.
A novel semi-analytic model is developed to determine interlaminar stresses in laminates including highly curved parts, for obtaining a rapid, accurate and reliable design tool for evaluating the reserve factor of a certain aeronautic composite component prone to unfolding failure.
Since ConA is a protein, it is prone to unfolding, aggregation, and degradation.
FALS variants of SOD1 are generally more prone to unfolding than hWT.
Second, in the unstable regime where proteins are prone to unfolding, protein evolution has two forms of selection.
At the same time, enhanced flexibility makes the enzyme more prone to unfolding 20 and reduces the overall activity.
However, some of the 5-repeat DC-SIGNR proteins may not be optimally oriented for binding, and it is possible that the dimers are more prone to unfolding under an applied force.
Protein lacking the Fe S cluster was less stable and more prone to unfolding, as demonstrated by a large decrease in secondary and tertiary content, and easily aggregated as it was found primarily in inclusion bodies.
A comparison of the backbone RMSD plots (Figure 5A) and the H-S distance of Tcur1278 (Figure 5E) over the complete MD simulation period indicated that the exposed flexible catalytic triad was also prone to local unfolding prior to the denaturation of the overall structure.
Systematic sampling of conformational states at five picoseconds (ps) intervals in a series of 27 independent 200 ps semi-quantitative MD simulations highlights the presence of distinct areas prone to local unfolding, with the most prominent peak centered around mjA' G810.
