Sentence examples for prone to transformation from inspiring English sources

It is also evident that somatic stem cells possess properties that may render them more prone to transformation.

Highly proliferative cells, such as progenitor cells, are more prone to transformation by aberrant gene expression of proto-oncogenes or tumour suppressor genes than terminally differentiated cells.

AID expressing B cells are prone to transformation (Robbiani and Nussenzweig, 2013) and mutation signatures of APOBEC homologues are found in the genomes of many cancer cells (Alexandrov et al., 2013; Burns et al., 2013; Taylor et al., 2013).

Furthermore, the relative abundance of different TDLU morphotypes in the human breast can influence breast cancer risk, where the least-differentiated TDLU type 1 (TDLU-1) is most prone to transformation [ 17].

A deeper understanding of how LKB1 restricts tumour formation, and the identification of the intestinal cell types most prone to transformation, are thus needed to allow the development of novel treatments for PJS, a disease for which there are presently no approved pharmaceutical strategies.

As previously shown cells that are manipulated to obtain an expanded replicative potential are prone to spontaneous transformation in culture.

Overall, wet co-milling with mannitol in an organic solvent followed by spray drying may be used as a formulation approach for producing respirable particles of water-soluble drugs or drugs that are prone to crystal transformation in an aqueous environment (i.e. formation of hydrates).

Transgenic mice that ubiquitously overexpress eIF4E show that distinct tissues, including the lungs, liver, and the lymphoid compartment, are more prone to oncogenic transformation (Ruggero et al, 2004).