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STAT3-KO mice were also more prone to the pathogenesis of age-related heart failure.
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These data suggest that T-cells that undergo clonal expansion are more prone to somatic mutations and that clones containing somatic mutations contribute to the pathogenesis of MS. How might variants in hnRNP A1 contribute to the pathogenesis of MS?
After backcrossing the original FVB/C57BL/6 line nine times and generating VC- and VC+ mice in a pure C57BL/6 background the deficiency of PPAR γin IEC resulted in worsened disease activity, greater weight loss and histological differences, suggesting that the Th1-prone genetic background of C57BL/6 mice is optimal for investigating the contribution of IEC PPAR γ to the pathogenesis of IBD.
Endothelial dysfunction might contribute to the pathogenesis of RCVS.
This may contribute to the pathogenesis of AML.
Ammonia is central to the pathogenesis of hepatic encephalopathy.
Dysregulated inflammation contributes to the pathogenesis of various diseases.
Ceramide-mediated apoptosis may contribute to the pathogenesis of mucositis.
Epigenetic mechanisms may contribute to the pathogenesis of complex diseases.
The renin-angiotensin system (RAS) plays a role in the pathogenesis of ARDS, Angiotensin II (Ang-II) contributing to the pathogenesis of inflammation and fibrogenesis.
Tendon vascularization represents the most important factor that attends to the pathogenesis of those lesions.
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