In addition, our results showed that Tol2 was less prone to integrate into retrotransposons (17 integration events) and tandem repeats (16 integration events).
The complexity of typically high-dimensional genomic data requires computational work prone to integrate different biological information sources through efficient model solutions.
Therefore, Tol2 is as prone to integrate into transcriptional units as other DNA transposons.
Further, 11% of the inferred HGTs in P. roqueforti clustered within 50 kb of the HTRs, suggesting that these genomic regions may be prone to integrate foreign DNA.
We also found that Tol2 was prone to integrate into AT-rich DNA regions and that a target site contained a weak palindrome-like consensus sequence.
Sequence analysis of integration sites revealed no strict specificity at the nucleotide level, but Tol2 was prone to integrate into AT-rich regions with weak palindrome-like consensus sequences.
The major diffusion of HPV in advanced lung cancer is conceivable as the lung cancer cells (originally HPV negative) are more prone to integrate HPV into the tumour genome than normal cells (Klein et al, 2009).
Unfortunately, the currently available episomal vectors for C. albicans [ 60, 61] replicate at low copy numbers, are very unstable, and are prone to randomly integrating into the host genome at a high frequency anyway.
The arrays prepared from smaller SiO2 spheres are prone to be densely integrated and top aggregation, while more defects and shorter periodicity are found for arrays from bigger spheres.
Consequently, we can suspect that further epidemiological work might redefine the acceptable threshold for cancer risks related to arsenic exposure and that the drinking water quality criteria for As are prone to be eventually revisited to integrate current and future knowledge on the problems caused by arsenic.
