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The highly specialized architecture of myelinated fibers renders them prone to functional disruption when any of the critical components are deranged.
However, many D. willistoni tRNAs do not have assigned orthologs in the other 11 species, and these unmapped loci may be more prone to functional changes.
This suggests that lysosomes in the tested panel of SCLC cells may be less abundant and/or have higher intra-lumenal pH and are therefore more prone to functional perturbations.
Both hypotheses are tenable, as PLP-dependent enzymes can display "catalytic promiscuity" (Han et al. 2001), and are extremely prone to functional divergence: More than 150 different enzymatic activities are currently listed in the PLP-dependent superfamily (fold-type I) to which SelA belongs (Percudani and Peracchi 2009).
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Closed multiple metacarpal fractures are considered highly unstable and are more prone to poor functional outcome.
Closed multiple metacarpal fractures are considered highly unstable and are more prone to poor functional outcome compared with open single metacarpal fracture [6, 7, 8, 9, 10].
Therefore, it is quite necessary to study miRNA-mRNA interactions using characteristic of miRNAs, especially homologous and/or clustered miRNAs are prone to have functional relationships.
In order to detect regions more prone to harbour functional promoters, we analysed the SIDD scores within the intergenic regions of BAp.
PCMOs are prone to acquire functional activities of hepatocyte-like cells (NeoHepatocytes) upon stimulation with appropriate differentiation media in vitro[ 2, 3], and in vivo following transplantation into mice [ 2].
Elderly persons with low muscle mass (LMM) or sarcopenia are prone to frailty and functional decline.
Elderly dialysis patients are prone to disabilities and functional decline.
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