Biophysical studies indicated that folded proteins need to (partially) unfold and expose aggregation-prone sequences to facilitate aggregation (Stefani and Dobson, 2003).
Interesting to note, we found HPV integration in the following fragile regions—(1p, 1q, 2p, 2q, 3p, 3q, 4p, 4q, 5p, 5q, 7q, 9q, 10q, 11p, 11q, 12p, 12q, 13q, 15q, 17q, 18q, 22q, Xp and Xq) that are prone to chromosome breaks to facilitate foreign DNA integration (Smith et al, 2006).
The rats were kept in a horizontal prone position for 30 min in order to facilitate the settling of blood in the basal cisterns.
UNICEF will ensure that agreements with existing partners operating in disaster-prone districts include an emergency response component to facilitate fast and effective response in times of emergency.
The dry season, with strong dusty winds and cold nights make people more prone to respiratory infections and facilitates the spread of bacteria.
Surgery was performed with the patient under brachial plexus anesthesia in the prone decubitus position with a perineural catheter for postoperative pain control and to facilitate physiotherapy.
This indicates that the induction of BIS was driven by the necessity to facilitate the clearance of aggregated proteins within an aggregation-prone milieu.
This mutation has been shown to facilitate the transition between the native state and a conformation that is prone to the formation of ordered aggregates, termed polymers [ 7].
Pif1 is known to facilitate the replication of DNA sequences that are rich in G bases and therefore prone to forming G-quadruplexes (Paeschke et al., 2011, 2013).
miRs may be less prone to degradation during formalin fixation, facilitating miR expression studies in formalin-fixed paraffin-embedded (FFPE) tissue.
