Sentence examples for prone to differentiation from inspiring English sources

Cells in a primed pluripotency state are more prone to differentiation and only naive pluripotent stem cells form germline chimera after injection into a blastocyst.

We further asked whether the cells with non-detectable globo-series glycolipids on the cell surface (SSEA-4 negative cell population) were more prone to differentiation.

Although cells with high Oct4 and Sox2 but low Nanog levels can in general be kept in an undifferentiated, pluripotent state, it has also been demonstrated that these cells are more prone to differentiation as compared to cells that express high levels of Nanog [11].

This profile is therefore associated with a less aggressive phenotype more prone to differentiation.

Therefore, our results indicate that H-CYLDWT cells are prone to differentiation in addition to presenting a high rate of apoptosis.

To determine whether Sox2 haploinsufficiency renders cells more prone to differentiation, we performed lineage tracing analysis using Sox9 ires-CreERT2/+ ; R26R EYFP/+ ;Sox2 βgeo/+ animals.

Mesenchymal stem cell differentiation toward the osteogenic or adipogenic fate is dependent on cell cell contacts, whereas isolated cells are less prone to differentiate [103].

Pediatric MSC appeared to be more prone to hepatocyte differentiation as co-culture with Huh-7 cells without hepatogenic differentiation medium was sufficient to induce albumin expression.

Evaluation of adipocyte lineage-specific transcripts and osteocyte lineage-specific transcripts showed that the expression of ALPL in MSCs in severe hypoxia is higher than in normoxia, indicating MSCs in hypoxia are more prone to osteogenic differentiation than in normoxia (Ejtehadifar et al., 2015).

Here, we discovered that several clones of ectopic, heterogeneous stem/progenitor cell populations isolated from human tooth pulp were particularly prone to myogenic differentiation.

However, the ES cells need to be maintained in inhibitory conditions to retain the undifferentiated state, because they are prone to spontaneous differentiation [ 58, 59].