However, our study indicates that, under a more realistic scenario of noisy, small, extinction-prone subpopulations, constant localized addition of individuals from the outside is not expected to have a major impact on the metapopulation dynamics, and that these results are generalizable.
Despite this accumulation, we show that in a heterogeneous culture the senescence-prone hMSC subpopulation has a lower proliferation potential and a higher incidence of aneuploidy than the non-senescent subpopulation.
One might speculate that the subsubtype A3 epidemic grew in a small subpopulation not as prone to migrate as compared to the subpopulations infected with the CRF02_AG.
The results further suggest that serologic screening conducted at enrollment may have selected a subpopulation more prone to EBV reactivation, such that mean percentage of seropositive conversion of seropositive group is significantly higher than seronegative group.
Measuring HbF does not address therefore the heterogeneous distribution of HbF within RBCs and hence subpopulations of RBCs prone to polymerisation, sickling and haemolysis because of their very low content in HbF.
Mobile home residents remain a vulnerable yet understudied subpopulation in regions prone to natural hazards (Kusenbach et al. 2010).
In rheumatoid arthritis, the subpopulation of CD14bright/CD16+ monocyte is expanded and prone towards generation of Th17 cells.
The sample of studied youth may be biased in that it is a subpopulation of young people who are more sexually active and therefore more prone to seek advice on STI and HIV.
These may not require a prone sleep position for their deleterious impact being associated with distinct causal pathways, or possibly indicating subpopulations yet to recognize the importance of the supine sleep position.
When applied to the United States, its outcome leads to the hypothesis that if indeed history repeats itself, some states or regions may be more greatly affected by GCC than others, not only because historically they are more prone to summer weather/climate-related diseases, but also because they contain a greater proportion of the sensitive subpopulations in the United States.
It would also allow meaningful comparison among different patient subpopulations and ethnic groups, and enable adequately powered, targeted studies on such groups that are less prone to between-center technical variability in results.
