A critical protein function lost from anywhere within this error-free repair BRCA pathway may force repair of DNA double strand breaks by lower fidelity, error prone methods.
However, as the mobility of the pedestrian is mostly controlled by vision in practice, an individual might detour slightly from the Euclidean shortest path connecting two given nodes (i.e., beeline path), as vision-based navigation is inherently an error-prone method.
The distribution of differences detected closely matched the expected distribution of errors and we conclude that, when undertaking gene discovery or assessment of genetic diversity using this error-prone method, it will be informative to empirically determine the rate of base misincorporation.
Lastly, quantification of smear patterns in autoradiograms is a quite error-prone method.
Prostate cancers with mutations to a protein called SPOP use an error-prone method to repair broken DNA strands.
There are two ways a cell can fill in this gap: an error-prone method using a translesion polymerase to copy the damaged template or an error-free method using the newly formed sister strand as a template (template switching).
Quantifying such a compensatory drop is a less bias-prone method for adjusting the incidence increase for lead-time effects, as it makes no assumption about the average lead time.
This can be done through the application of the Bayes theorem, which few doctors are capable of doing [ 15], or by using natural frequencies, an easier and less error-prone method [ 22].
On the one hand, they can provide mechanisms to alleviate the lack of support for decentralized and automated management of access control and authorization policies, which are usually configured using inefficient and error-prone methods.
Gene fusions or other rearrangements often found in some of these tumors bear witness to a double strand break repaired by error-prone methods.
Although the EFSA stressed the necessity of identifying categories of foods that may pose a risk for human health with respect to cereulide contamination [ 4], a comprehensive evaluation of food matrices was hampered due to laborious, time-consuming, and error-prone methods to quantify cereulide amounts in foodstuffs.
