The protein normally cleans up after cells with damaged DNA by clamping down on cell division or prompting cell suicide; without it, cancer cells proliferate.
Later, elevated levels of ROS became synonymous with genomic instability prompting cell death or carcinogenesis.
Inhibition of MDM2 should result in increased levels of p53, prompting cell-cycle arrest, apoptosis, and possibly enhanced chemosensitivity in breast tumors with wild-type p53.
The method can also prompt cells to become nonembryonic cell types.
Other proposals include growing structural parts of buildings and street furniture around frames, using synthetic biology to prompt cells to produce useful materials.
In an elegant study in live mice, they prompted cells to make the leap directly from one mature cell into another flouting the usual rule that development of cells is a one-way street.
The researchers showed that BPA is an active agent that can prompt cells to become fat cells.
"Yet to her great surprise, Kirste found that two hours of silence per day prompted cell development in the hippocampus, the brain region related to the formation of memory involving the senses".
HBx can prompt cell cycle regulatory pathways and apoptosis [ 55].
We previously reported that MGr1-Ag could prompt cell adhesion-mediated GC drug resistance through interaction with LN.
