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Without prompt closure, warned Senator Gordon H. Smith of Oregon, "we will have an aftertaste that will never go away".
Group 1, prompt closure, was the baseline group in our analysis.
It might be argued that the prompt closure during these outbreaks was beneficial.
However, in outbreaks where wards were not closed, the length of outbreaks were similar to the prompt closure group and also had fewer patients and staff affected and fewer cases per day of outbreak compared with prompt closure.
Our results support recommendations made after the first wave of outbreaks in 2013 (3 ), which suggest that prompt closure of markets could lead to substantially fewer infections.
In the study by Lopman et al, the wards that were in the prompt closure group accounted for only 14% of the outbreaks analysed.
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Moreover, the non-prompt closure group was comprised of outbreaks where wards were not closed and those that closed later than 3 days.
Regression analysis indicates that after controlling for season ward size and type, the duration of outbreak and duration of disruption were shorter, fewer patients were affected by the time of closure and fewer patients were affected overall, when closure occurred promptly (within 3 days of the first case becoming ill) compared with non-prompt closure groups.
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