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Sequential images showed prompt accumulation of platelet-associated radioactivity in areas within the right hemithorax which corresponded to certain tumors noted on the chest roentgenogram.
Increases in fat mass prompt accumulation of macrophages in WAT [ 4, 7] which produce a number of chemokines and cytokines [ 27].
Important features in the latter regard would be (1) the prompt accumulation of seminal components at the utero-tubal junction due to the influence of powerful myometrial contractions [ 18- 20] and (2) the extremely prominent underlying lymphatic 'vessels' during oestrus [ 21].
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We are using a systems biology approach to try and determine the primary event in the decline in proteolytic capacity with age and whether there is in fact a vicious cycle of inhibition, with accumulating aggregates further inhibiting proteolysis, prompting accumulation of aggregates and so on.
Thus, TRAP1 is oncogenic not only by prompting accumulation of the oncometabolite succinate and the ensuing pseudohypoxic response (i.e., HIF1 activation in normoxic conditions), but also by shielding tumor cells from ROS-induced PTP opening and death.
The same genes showed a prompt γH2AX accumulation during the early stage of DDR which then decreased over time as DDR proceeded.
siRNA-mediated knockdown of HIF2α promoted p53 activity in human tumor cells and induced cell death by disturbing the cellular redox homeostasis and prompting the accumulation of ROS.
These data suggest that GA sensitises CDDP to NSCLC cells through inhibiting CDDP-induced HO-1 upregulation and then afterwards prompting the accumulation of ROS.
With its high binding affinity for albumin, tumoral SPARC prompts the accumulation of albumin in tumors and increases the effectiveness of albumin-bound drugs.
CO2 stress removal was marked by both a rapid upsurge in the ratio of unfreezable water to total water and an osmotic adjustment prompted by the accumulation of soluble sugars, 1-kestose, raffinose and galactinol.
In particular, Aminopielik D 450 SL and Chwastox 300 SL prompted heavy metals accumulation in roots as indicated by their high transfer coefficients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com