Sentence examples for promoting target from inspiring English sources

The coordination of the 5' phosphate involves residues of the (R YREK motif that is common to the IS4 transposase family, and stabilizes a DNA conformation that dramatically enhances strand transfer of the donor DNA into the target by promoting target DNA capture and/or the strand transfer reaction itself [22].

MicroRNAs (miRNAs) are short 20 22 single strand regulatory RNAs that function by inhibiting translation of their targets or promoting target RNA degradation [ 11, 12].

In contrast, LSD1 can associate with nuclear hormone receptors such as the androgen or estrogen receptor [ 69, 87], and in these situations LSD1 shows H3K9me2 demethylase activity, thereby promoting target gene transcription.

In 2007, several groups identified Ubiquitously Transcribed Tetratricopeptide Repeat on chromosome X (UTX) and Jumonji D3 (JMJD3) as novel histone demethylases that catalyze the removal of di- and trimethyl groups on histone H3 lysine 27, thereby promoting target gene activation.

ERβ, however, holds low trans-acting capability on ERE-containing estrogen target genes and alpha/beta heterodimers are less efficient than ERα homodimers in promoting target genes activity [ 10].

Much of the activity of RTA3 can be recovered in RTA3-C15L, indicathat thet the C15 residue functions largely as a bulky hydrophobic side chain promoting target cell membrane interactions.

Our data reveal critical and novel roles for CNTN4/APP in promoting target-specific axon arborization, and they highlight the importance of this process for functional development of a behaviorally relevant parallel visual pathway.

Since ALT-PTK6 led to repression of the β-catenin/TCF luciferase reporter (Figure 3B), we examined the impact of ALT-PTK6 expression on the growth promoting targets of β-catenin/TCF.

The observed effects of syntaxin proteolysis on docking may in part be indirect, by promoting targeting and local accumulation of docking factors, such as Munc18-1, at putative docking sites.

Some ways in which antisense therapy could reverse the pathology of myotonic dystrophy include: neutralization of binding sites for RNA-binding proteins, promoting targeted degradation of repeat expansion mRNA, and reduction in the size of the trinucleotide expansion.

It will also have an arcade featuring "virtual shooting" games intended to promote target shooting and hunting, Mr. LaPierre said.