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An alternative model, however, is that an accumulation of risk alleles at non-coding loci, each with minor effects on TF/uDBP-PRE interaction, has an aggregate effect promoting susceptibility in those individuals with the greatest cumulative risk allele burden (Figure 8B).
The mechanisms promoting susceptibility of people with HIV to TB disease are incompletely understood.
The mechanisms promoting susceptibility of people with HIV to tuberculosis disease are incompletely understood, being likely caused by multifactorial processes.
The evidence in this paper indicates that activation of the auxin signaling pathway does not promoting susceptibility of Ponkan mandarin after infection with the bacterium.
EVs uptake by other parasites was reported to trigger life cycle transitions and to be involved in promoting susceptibility to infection of host cells [ 17, 18].
Renewed global interest led to advances in recognising TB/HIV co-infection and understanding the mechanisms promoting susceptibility of HIV-infected people in developing TB disease as part of a multifactorial process [ 26- 30].
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Both genes have lower expression in susceptible strains, again suggesting that lowered overall DNA damage response promotes susceptibility.
It may even have promoted susceptibility to the virus it was trying to curb.
It has been previously shown that genetic or environmental factors, which promote susceptibility to allergic conditions, prevent the development of Th1-mediated inflammatory disease of multiple sclerosis (MS).
We hypothesised that the intracellular effects of EPEC infection could promote susceptibility to cancer.
We hypothesised that the effects of EPEC infection on the host cell could promote susceptibility to cancer.
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