Sentence examples for promoting sensitivity from inspiring English sources

We conclude that the mechanisms of rapamycin resistance in hepatic cells involve alterations of signaling downstream from mTOR and that the mechanisms are highly heterogeneous, thus predicting that maintaining or promoting sensitivity will be highly challenging.

Most cancer treatments induce autophagy in the remaining, resistant cancer cells, with inhibition of autophagy promoting sensitivity to therapy.

Consequently, antiestrogens, such as tamoxifen, inhibit endogenous Bcl-2 expression in breast cancer cell lines, promoting sensitivity to cytotoxic anticancer drugs such as doxorubicin.

Swapping the identities of nearby residues between these two isoforms generated more robust PrxII variants and also more sensitive PrxIII variants, although again it was the presence of the C-terminal YF positions that was most critical to promoting sensitivity.

When the beat frequency between the pump and the Stokes beams matches a Raman active vibrational mode Ω R of the molecules or lattice in the sample, a strong and coherent anti-Stokes signal is generated, greatly promoting sensitivity with chemical selectivity.

Although not well understood, induction of intracellular UA accumulation in pancreatic cancer cells (PANC-1) following radiation exposure or treatment with 5-fluorocracil was found to mediate the induction of MHC class-I related proteins MICA/B that in turn promoted sensitivity to NK-92 cell killing[152].

The result is an integrated activation that promotes sensitivity transitions and the signals are then perceived.

In our opinion, the result is an integrated activation that promotes sensitivity transitions and the signals are then perceived.

It is therefore likely that therapeutic approaches that aim to normalize the tumor microenvironment and/or interrupt the crosstalk between the tumor cells and the microenvironment, will not only help to stall the progression of cancer, but also have a potential to promote sensitivity of tumors to chemotherapy or radiotherapy.

Oncogenic transformation promotes sensitivity to inhibition of certain metabolic pathways (synthetic lethality).

The solvent system and sample preparation were carefully selected to reduce the matrix effect on ionization and promote sensitivity.