Sentence examples for promoting apoptosis from inspiring English sources

Nevertheless, the fundamental mechanisms by which BCL2-type proteins shift from inhibiting to promoting apoptosis remain poorly understood.

Such cells are functionally more resistant to danger signals received through TLRs, promoting apoptosis of effector T cells and generating Tregs.

Biflorin causes single and double DNA strand breaks, consequently inhibiting cell cycle progression, replication and DNA repair and promoting apoptosis.

X-Linked inhibitor of apoptosis protein (XIAP) is a promising molecular target for the design of new anticancer drugs aiming at promoting apoptosis in cancer cells.

Cells under hypoxic stress either induce an adaptive response that includes increasing the rates of glycolysis and angiogenesis or undergo cell death by promoting apoptosis or necrosis.

MicroRNA miR-124 has been suggested as a tumor suppressor for its role in inhibiting cell growth, inducing differentiation and promoting apoptosis.

These toxins decreased the viability of cells by inducing intracellular reactive oxygen species (ROS) production and promoting apoptosis in the BRL 3A cells.

Corroborating the present findings, You and colleagues36 found that excess of iron in the substantia nigra increased oxidative stress levels, promoting apoptosis through the Bcl-2 / Bax pathway and the activated Caspase3 pathway in an animal model of PD.

These results suggested that PAC-csMSN plays an important good role in promoting apoptosis.

Together, these studies suggest MELK may have a critical role in promoting apoptosis in developmental models and some forms of cancer.

This conjugation was capable of showing high antileukemic activity by inducing cell cycle arrest and promoting apoptosis regulating activities like nuclear fragmentation.