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However, the observed enrichment of transcripts with structured UTRs is not related to a particular structure, hence, it is unlikely that a particular RNA binding protein that promotes transcript stability by binding to a specific structured RNA motif is responsible for the broad expression pattern.
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The performed analysis takes into account the level of agreement between the methods and promotes transcripts with significant differences in all of them.
TFIIS, in addition to its established role in promoting transcript cleavage, is found to relieve arrest by a second, cleavage-independent mechanism.
3'UTRs are recognized and targeted by small non-coding miRNAs that inhibit translation, promote transcript degradation, and often act as tissue-specific regulators of transcript stability [45].
However, inefficient splicing might promote transcript degradation and reduce pre-mRNA levels.
Alternative splicing (AS) is thus a mechanism that enables multiple transcripts and proteins to be encoded by the same gene, thereby promoting transcript and protein diversity [ 1].
In general, miRNAs, together with other players in the RNAi pathway, negatively regulate gene expression either by repressing translation or by promoting transcript degradation.
MicroRNAs (miRNAs) are a class of small non-coding RNAs (ncRNAs) that bind to target mRNAs and promote transcript degradation and/or inhibit translation [ 10].
RNMT and the methyl cap increase transcript abundance by promoting transcription and by stabilizing transcripts [ 21, 22].
b, Exogenous cytokinin application rapidly promotes the transcript level of PEAR genes, including PEAR2, DOF6 and TMO6.
This complex targets Ser-2 residues of the CTD and promotes productive transcript elongation subsequent to its recruitment to the RNA pol II complex [15].
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