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In the TNF α-activated NF- κB pathway, TRAF2/5 catalyzes K63-linked ubiquitination of receptor-interacting protein 1 (RIP1) and subsequently promotes the interaction between RIP1 and NEMO.
(C) PLP2-TM promotes the interaction between Beclin1 and STING.
The ECM promotes the interaction between individual cells and between different cell types, and increases the strength and resilience of the tissue in mechanically dynamic environments.
WAC promotes the interaction between TTT and Pontin/Reptin in an energy-dependent manner, thereby promoting mTORC1 activity by facilitating mTORC1 dimerization and mTORC1-Rag interaction.
We show that Crb3 promotes the interaction between Yap and the Hippo pathway kinases Lats1/2 at apical cell junctions to induce Yap phosphorylation and cytoplasmic retention, which drive cell differentiation.
ABA binds to the pyrabactin resistant-like/regulatory components of ABA receptors, PYL/RCAR (hereafter referred to as PYLs for simplicity), an ABA receptor family that promotes the interaction between PYL with protein phosphatase 2C (PP2C), which then results in the release of SNF1-related protein kinase (SnRK)) from the repression of PP2C.
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Phosphorylated MuSK then interacts with dok-7, effectively increasing AchR postsynaptic gathering, promoting the interaction between AChR and Rapsyn in the newly formed NMJ [ 35, 36], stabilizing the AchR, and slowing the decomposition of the AChR.
In our previous study, we demonstrated that HSCARG interacts with IKK β and suppresses its phosphorylation by promoting the interaction between PP2A and IKK β, which provided one of the possible mechanisms to explain how HSCARG inhibits IKK β phosphorylation and NF- κB activity.
Low pH leads to protonation and neutralization of carboxyl groups in the extract promoting the interaction between the AuCl4- ion and the biomolecule.
Our data revealed that PCNA NEDDylation occurred later than its ubiquitination, ubiquitin but not NEDD8 could promote the interaction between PCNA and polη.
Under hypoxic stress, Tyr18 is dephosphorylated to promote the interaction between FUNDC1 and LC3B and mitophagy is triggered (Liu et al., 2012).
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