Sentence examples for promotes the activation of from inspiring English sources

The activated MLKL promotes the activation of plasma membrane permeabilization (PMP) and then triggers the necrosis.

The activated caspase-8 promotes the activation of caspase-3, which in turn induces the characteristics of apoptosis.

SH2B1 β enhances JAK2 activity and promotes the activation of several downstream networks like STAT3 and phosphatidylinositol (PI) 3-kinase pathways [ 18, 39].

Generally, mTORC2 phosphorylates and activates Akt, which promotes the activation of mTORC1 through the Ras family protein Rheb.

Schematic diagram is presented in Figure 5. DIM triggers cytochrome c translocation from the mitochondria to the cytosol, which promotes the activation of caspase 9, that activates in turn caspases 3 and 6 in a time-dependent manner.

Upon entry into S phase, increase in the activities of CDK and DDK promotes the activation of licensed origins.

Free Gβγ recruits the scaffold protein Ste5 to the plasma membrane, which promotes the activation of the MAP3K Ste11 and in turn activates the MAP2K Ste7.

For example, p53 activation seems to inhibit the activity of mammalian target of rapamycin (mTOR) and consequently promotes the activation of autophagy proteins [ 96].

NETs can also activate the intrinsic coagulation pathway by activating FXII to form FXIIa [ 20], which then promotes the activation of complement pathways.

β-catenin also recruits the acetyltransferase p300 to IRF3 and promotes the activation of the IFN-β enhanceosome.

The phosphorylation of insulin receptor substrates further promotes the activation of phosphotidylinositol 3-kinase and, subsequently stimulation of Akt and its downstream mediator AS160.