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Literature reveals that interaction with live Staphylococcus aureus (S. aureus) or heat killed S. aureus (HKSA) promotes secretion of CXCL-8 or interleukin-8 (IL-8) from leukocytes, however, the expressions of CXCR1 in murine splenic (SPM), peritoneal macrophages (PM) and resident fresh bone marrow cells (FBMC) have not been identified.
Additionally, it has been recently identified a novel transcription factor encoded by the rv3849 gene which promotes secretion of ESX-1 substrates, including ESAT-6 [36], and hence was renamed EspR, an acronym for ESX-1 secreted protein regulator.
A T2SS is present in at least 16 environmental non-pathogenic bacteria [1] where it promotes secretion of enzymes such as lipases in Acinetobacter calcoceticus and Pseudomonas alcaligenes [2], [3] or chitinase in Escherichia coli K12 [4].
In addition to VEGF, HIF activation promotes secretion of the pro-angiogenic urokinase plasminogen activator (uPA) [ 68, 69].
This indicates that chemerin21-157 promotesecretionof of enzymes that digest the extracellular matrix, leading to deterioration of cartilage tissue.
We conclude that signaling through IFN I promotes secretion of key inflammatory cytokines, which accelerate progressive lung pathology.
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Senescent cells secrete HMGB1 promoting secretion of inflammatory cytokines (TNFα, IL-1β and IL-6) by macrophages [ 55].
These studies indicate that while the SP is very important in promoting secretion of the scFv, it had little influence on increasing scFv secretion levels even when both the TEV and the KDEL sequences significantly increased overall protein levels.
More importantly, AMF inoculation ameliorated inhibitory effects of ZnONPs by promoting secretion of glycoprotein called glomalin a potent metal chelator within the rhizosphere, which significantly reduced (by almost half) Zn uptake by root and subsequent translocation to the shoot.
Further in vitro experiments using functionalized microspheres with surface integrated RGD peptide activate co-cultured skeletal populations in pellets and promote secretion of extracellular matrix collagens and human osteocalcin.
Moreover, using cocultured cells (DPSCs/CCN3 and DPSCs) in vitro and the cocultured cells-poly (lactic-co-glycolic acid) (PLGA) scaffold complex in vivo, we demonstrated that CCN3 was capable of promoting mineralization in a non-cell autonomous manner through promoting secretion of BMP2.
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