Exact(24)
We extend these findings by providing experimental evidence that VEGF-induced activation of the Notch signaling pathway attenuates KDR expression in KDR+ mesodermal precursors and EPs, permits differentiation of KDR+ precursors into non-endothelial lineages (vascular SMCs and cardiomyocytes), and promotes maturation of EPs to mature ECs during hPSC differentiation.
This same hormone has been demonstrated in the ovaries of the closely related sea urchin, where it also promotes maturation of the oocyte.
Nicotinamide promotes maturation of IPCs in the last stage.
Shank1b promotes maturation of dendritic spines [19], while its dominant negative mutant causes a reduction in spine size and density [20].
Removal of IL-7 promotes maturation of the cultured pro/pre-B cells into immature B cells which express surface IgM [51] and κLC on their cell surface.
Although unlike apoptotic cells, necrotic cells promotes maturation of DCs [26], [27], we detected minimum proliferation of splenic 1H3.1 T cells in vivo following infusion of necrotic BALB/c splenocytes (Fig. 2C).
Similar(36)
Expression in the presence of cyclosporine A promoted maturation such that mature 170 kDa P-gp became the major product (∼90% of total P-gp).
It was observed that the presence of 10 μM cyclosporine A promoted maturation of both mutants to yield the mature form of P-gp as the major product.
Because mechanical loading increases during development and facilitates cardiac maturation, we hypothesized that afterload would promote maturation of EHTs.
Low-dose DTX did not negatively affect iDC viability and instead promoted maturation and IL-12 production.
The first injection was done to promote maturation of the eggs and the second one was to induce the release of eggs from the ovary (Shan Jian 1985).
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