Sentence examples for promotes an interaction from inspiring English sources

Finally, variant peptide binding to TNF-α may modify the surface of TNF-α in such a way that promotes an interaction between TNF-α and specific E.coli protein(s).

ER stress induces GRP78 expression and promotes an interaction between GRP78 and AKT, as shown by an in situ proximity ligation assay (PLA) and co-immunoprecipitation, which in turn suppresses Ser473 phosphorylation and thereby modulates substrate specificity.

It has been reported that during mitosis, Kap121 blocks Ulp1's access to its NPC-binding site and thus promotes an interaction of Ulp1 with septins [ 27].

In most of the studied GPCRs, binding of the sensed ligand molecule (agonist) causes a conformational change in the helical bundle that promotes an interaction with a GTP/GDP binding protein, which then triggers the intracellular signal cascade [ 4, 5].

The importance of the MEP-1 DNA-binding protein in NuRD-mediated repression of LIN-3/EGF was revealed by the discovery that LIN-1 is sumoylated and that this modification promotes an interaction with MEP-1, thus stabilising NuRD activity on LIN-1 target promoters [ 17 ].

Intriguingly, phosphorylation of Munc18c has recently been shown to decrease its interaction with Sx4 and promote an interaction with Doc2β [34].

In summary, our results indicate that disruption of actin filaments promoted an interaction between mitochondrial Ca2+ and cytoplasmic Ca2+, as generalized in our model.

The degree of functionality gives the total number of accessible regions in the sequence that may promote an interaction with another RNA molecule.

Taken together, these results indicate that a central domain of Tpz1 encompassing amino acids 243 420 is sufficient to promote an interaction with Stn1 and that this interaction is stabilised by Ten1.

Although we, of course, cannot rule out that the interaction between Rif1 and PP1 proteins in either species is indirect, these results suggest that the PP1 docking motifs in Rif1 are functional and promote an interaction with the PP1 phosphatases.

Overall, the results suggest either that the export of Upf3p occurs by binding to Upf2p or a specific export pathway for Upf3p is necessary to promote an interaction with Upf2p.