Sentence examples for promoters classes from inspiring English sources

Interestingly, we find that active enhancers (Classes III, VII, VIII, IX) have higher levels of H3K18ac and H3K27ac than active promoters (Classes V and VI) (Fig.  1g).

Our search strategy revealed that, as expected, CBP binds to active promoters (Classes V and VI) and active enhancers (Classes III, VII, VIII and IX).

Moreover, these multiple cTFBSs are more dominant in genes from class (C1 and C3) known to be responsive to estrogen, as well as genes with ERE predictions in their promoters (class C2).

In addition, these genome-scale strategies will delineate promoter sequences, promoter classes, and identify those genes that are co-regulated.

Here, we show that promoter classes are significantly differentiated by nucleosome organization and chromatin structure.

Our results show that promoter classes defined from 5' capped transcripts not only reflect differences in the initiation process at the core promoter but also are indicative of divergent transcriptional programs established within gene-proximal nucleosome organization.

Previous studies have explored the presence of genomic features, such as CpG islands and sequence motifs, in these promoter classes, but virtually no studies have directly investigated the relationship with chromatin features.

The application of deep sequencing to map 5' capped transcripts has confirmed the existence of at least two distinct promoter classes in metazoans: "focused" promoters with transcription start sites (TSSs) that occur in a narrowly defined genomic span and "dispersed" promoters with TSSs that are spread over a larger window.

We show some additional interaction groups, both between promoter classes and within each promoter class.

Certain ontologies were represented in specific promoter classes.

Distinct nucleosome positioning in particular promoter classes was revealed.